Abstract: This article considers why turn-of-the-twentieth-century U.S. women’s suffragists failed to build a coalition with anti-imperialists comparable to the antislavery-women’s rights alliance of the antebellum period. Although some prominent suffragists–including Susan B. Anthony and Elizabeth Cady Stanton–accepted the fundamental principle of empire and only critiqued the implementation of U.S. policies, others regarded anti-imperialism as a necessary outgrowth of their suffrage principles. Since imperial endeavors gave rise to an anti-imperialist movement, that, during the Philippine-American War, gained more political salience than women’s suffrage, anti-imperialist suffragists also regarded their opposition to empire as a politically astute strategy. Yet the suffragists who strove to build a reform coalition were frustrated by both male anti-imperialist leaders and many of their suffrage associates. And despite their interest in coalition building, anti-imperialist suffragists failed to reach out to Filipina women, who faced protracted struggles for political rights.